Search results for "Crucial point"
showing 5 items of 5 documents
Government Performance, Ethics and Corruption in the Global Competitiveness Index
2017
Public administration efficiency is an up to date topic. More in depth, the crucial point is how it is related, on the one hand, with a disruptive phenomenon like corruption and, on the other hand, with ethics. This study aims to show how public sector performance is affected by ethics and corruption. In order to explain such a relationship, this research run a cross-country analysis, where indices of public-sector performance are juxtaposed with corruption levels.
An update on the conquests and perspectives of cardio-oncology in the field of tumor angiogenesis-targeting TKI-based therapy.
2019
Introduction: The angiogenesis mechanism is considered a crucial point in neoplastic development. A growing number of multi-targeted tyrosine kinase inhibitors (TKI) has been developed and approved for cancer treatment during the last few years. Cardiac side effects still remain an issue to manage nowadays. These drugs mechanisms and toxicities have already been discussed, hence the authors will report updates on these already available drugs. Area covered: This manuscript provides an updated review on the new mechanisms involved in angiogenesis and cardiotoxicity that are TKI-related. Here is reported an overview of the already available and the most recent TKIs under investigation in the …
Material sources of the Roman brick-making industry in the I and II century A.D. from Regio IX, Regio XI and Alpes Cottiae
2015
International audience; Bricks, fine pottery, ceramic gears and tiles are among the human-made objects routinely recovered in archaeological documentation. Sites associated with early civilizations can provide thousands of samples from a single excavation. They come in endless varieties according to economic and social circumstances and, as debris can last almost forever, provide important clues about the past behaviours in human societies. Any information about the provenance of ceramics is highly valuable in archaeological analysis. In the case of Roman brick-making, the provenance and manufacture of clayey materials are usually interpreted only by studying stamps imprinted on the artefac…
Rules and norms: two kinds of normative behaviour:
2016
Celano’s notion of a “pre-convention” is grounded in the opposition between two allegedly different kinds of normative behaviour: observing a “rule” and conforming to a “norm”. This opposition plays a central role in Celano’s paper, and marks a crucial point in his intellectual trajectory. Nevertheless, it remains largely implicit. In this paper, I try to make it fully explicit, giving a more precise characterisation of both kinds of normative behaviour. I also focus on the importance of distinguishing between them, express some conjectures (or wishes) regarding Celano’s future research, and propose a (marginal) criticism.
Las penúltimas razones de la moralidad en Tugendhat
2017
RESUMEN. El trabajo explora críticamente la idea de una justificación débil o penúltima de la moral enmarcándola en el conjunto de la filosofía de Tugendhat, reordenan do sus escritos éticos y discriminando los diversos aspectos que incluye dicha idea. Entre ellos, revisa el concepto formal de moral, ligado a los sentimientos, antes de centrarse en el punto crucial: la fundamentación de la ética moderna. Aquí se distingue, por un lado, la justificación comparativa de un contractualismo igualitario frente a otras alternativas teóricas y, por otro, los motivos que pueden llevar (more heideggeriano, en realidad) a un individuo autónomo a entenderse en términos morales. ABSTRACT. This paper exp…